產(chǎn)品名稱：Anti-Human CD10 FITC (eBioCB-CALLA) 100 tests 產(chǎn)品貨號：eBioscience 11-0106-42 產(chǎn)品規(guī)格：100 tests Anti-Human CD10 FITC Also known as: Common Acute Lymphocytic Leukemia antigen, Neprilysin, CALLA, NEP, Mme Clone: eBioCB-CALLA (CB-CALLA) RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 11-0106 Cat. No. Size 11-0106-41 25 tests 11-0106-42 100 tests Description: The eBioCB-CALLA monoclonal antibody recognizes human CD10 (CALLA, NEP, enkephalinase, Neprilysin), which is a 100 kDa, type II cell surface glycoprotein originally identified for its expression on most acute lymphoblastic leukemias (ALL). Subsequently, CD10 was shown to be the same molecule as the neutral endopeptidase (NEP), or KII-NA. CD10 is a Zn2+-dependent metallo-peptidase with endothelin, glucagon, gastrin, neurotensin and bradykinin included among its substrates. CD10 is involved in the regulation of chemotactic and inflammatory processes involving neutrophils. In B cells, CD10 regulates stromal cell-dependent B lymphopoiesis and expression has also been reported on mature B cells in germinal centres. In addition to the hematopoietic compartment, other major sites of CD10 expression are the brush border of enterocytes and renal tubules and glomeruli. There is partial blocking of the eBioCB-CALLA and MEM-78 monoclonal antibodies indicating that they recognize similar epitopes.
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