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產品名稱:anti-mouse CD106 FITC 429 100 ug
產品貨號:eBioscience 11-1061-82
產品規格:100 ug
Anti-Mouse CD106 (VCAM-1) FITC
Also known as: VCAM1
Clone: 429
RUO: For Research Use Only. Not for use in diagnostic
procedures.
SKU# 11-1061
Cat. No. Size
11-1061-81 50 ug
11-1061-82 100 ug
11-1061-85 500 ug
Description: The 429 monoclonal antibody reacts with mouse CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to integrin α4β1 (VLA-4, CD49d/CD29) and Integrin a4b7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.