產(chǎn)品名稱：Anti-Human CD109 PE (HU17) 100 tests 產(chǎn)品貨號(hào)：eBioscience 12-1099-42 產(chǎn)品規(guī)格：100 tests Anti-Human CD109 PE Also known as: CPAMD7, 150 kDa TGF-beta-1-binding protein Clone: HU17 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 12-1099 Cat. No. Size 12-1099-41 25 tests 12-1099-42 100 tests Description: The HU17 monoclonal antibody reacts with human CD109, also known as the platelet-specific Gov antigen. CD109, a GPI-anchored monomeric glycoprotein, exists in two isoforms of 120 and 150 kDa, which are proteolytically degraded from a 170 kDa form. CD109 is expressed on activated T cells, activated platelets and endothelial cells. CD109 expression is also found on a subset of CD34+ cells in ***** and fetal bone marrow which contain megakaryocyte, myeloid, erythroid and multilineage progenitors, as well as pluriopotent hematopoietic stem cells. Recently, it has been demonstrated that CD109 is expressed on a variety of human cancer cell lines, and also lung and esophogeal cell carcinomas. In addition, CD109 was recently found to be a negative regulator of TGF-β in keratinocytes.
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