產(chǎn)品名稱：Anti-Human CX3CR1 (2A9-1) PE, 100 tests 產(chǎn)品貨號：eBioscience 12-6099-42 產(chǎn)品規(guī)格：100 tests Anti-Human CX3CR1 PE Also known as: Chemokine C-X3-C receptor 1, V28 Clone: 2A9-1 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 12-6099 Cat. No. Size 12-6099-41 25 tests 12-6099-42 100 tests Description: This 2A9-1 monoclonal antibody reacts with human CX3CR1, which is the receptor for fractalkine, a transmembrane chemokine of the CX3C family. CX3CR1 is a seven transmembrane G protein-coupled receptor expressed on CD16+ NK cells, T cells (e.g. CD8+, CD4+, and gamma/delta), and monocytes. In non-immune cells, CX3CR1 has been found on osteoclast precursors and microglia. Little to no CX3CR1 surface expression can be detected on B cells and granulocytes. Together, fractalkine and its receptor mediate cell-cell adhesion and chemotaxis of NK cells, T cells, and monocytes. The expression of CX3CR1 has also been correlated with high levels of intracellular perforin and granzyme B.
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