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產(chǎn)品名稱:Anti-Human CD156c (ADAM10) (clone OV1F12) PE, 25 tests
產(chǎn)品貨號(hào):eBioscience 12-6319-41
產(chǎn)品規(guī)格:25 tests
Anti-Human CD156c (ADAM10) PE
Also known as: Disintegrin and metalloproteinase domain-containing protein 10
Clone: OV1F12
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-6319
Cat. No. Size
12-6319-41 25 tests
12-6319-42 100 tests
Description: This OV1F12 (1F12HE) monoclonal antibody reacts with human CD156c, which is also known as a disintegrin and metalloproteinase domain-containing protein (ADAM) 10. This type I transmembrane glycoprotein is expressed ubiquitously on hematopoietic and non-hematopoietic cell types. Studies demonstrate that CD156c expression is regulated by PAX2 in cancer cells. CD156c plays a critical role in hematopoiesis, including lymphocyte development, and autoimmunity by regulating the shedding and secretion of various receptors and chemokines, including Notch, CD23, CXCL16, and the IL-6R. Finally, deregulated CD156c expression has been associated with T-cell acute lymphoblastic lymphoma (T-ALL) and Alzheimer’s disease.