產(chǎn)品名稱：Anti-Mouse Egr2 PE (erongr2) 25 ug 產(chǎn)品貨號(hào)：eBioscience 12-6691-80 產(chǎn)品規(guī)格：25 ug Anti-Mouse Egr2 PE Also known as: Krox-20 Clone: erongr2 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 12-6691 Cat. No. Size 12-6691-80 25 ug 12-6691-82 100 ug Description: This erongr2 monoclonal antibody recognizes mouse early growth response 2 (Egr2, Krox-20). Egr2 is a zinc finger-containing transcription factor that is important for the development of T cells and NKT cells. Egr2 is predominantly expressed in the thymus and nervous system, and it is also upregulated in T cells following TCR-crosslinking. Upregulation in all non-adherent mouse splenocytes has been observed following stimulation with phorbol 12-myristate 13-acetate (PMA) and ionomycin. Egr2 is believed to antagonize T cell activation and has also been reported to promote apoptosis. The erongr2 antibody also appears to modestly stain a subpopulation of T cells and B cells in freshly isolated spleen cells. The erongr2 monoclonal antibody is specific for Egr2 and does not crossreact to Egr3, based on immunoblot analysis.
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