產(chǎn)品名稱：Anti-Human G-CSF (clone 8F5CSF) PE, 100 tests 產(chǎn)品貨號：eBioscience 12-7351-42 產(chǎn)品規(guī)格：100 tests Anti-Human G-CSF PE Also known as: Granulocyte colony-stimulating factor Granulocyte colony-stimulating factor, CSF3, Pluripoietin Clone: 8F5CSF RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 12-7351 Cat. No. Size 12-7351-41 25 tests 12-7351-42 100 tests Description: G-CSF (Granulocyte colony-stimulating factor) is a growth factor that stimulates the proliferation, differentiation, and mobilization of hematopoetic stem cells. It is expressed by monocytes, macrophages, and bone marrow stromal cells, and can also be induced in fibroblasts by IL-17A. Unlike GM-CSF and IL-3, which can stimulate cells of multiple lineages, G-CSF activity is limited to neutrophilic granulocytes. G-CSF is essential to the maintenance of neutrophil counts during homeostasis, and low basal levels of the protein are detectable in the serum of healthy individuals. Circulating levels become elevated rapidly upon infection, as G-CSF is also important for the activation and mobilization of mature neutrophils during the innate immune response. G-CSF therapy is commonly used to treat neutropenia following bone marrow transplant or chemotherapy.
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