產(chǎn)品名稱：Anti-Human Podocalyxin PE (B34D1.3) 25 tests 產(chǎn)品貨號(hào)：eBioscience 12-8873-41 產(chǎn)品規(guī)格：25 tests Anti-Human Podocalyxin PE Also known as: Gp200 Clone: B34D1.3 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 12-8873 Cat. No. Size 12-8873-41 25 tests 12-8873-42 100 tests Description: The monoclonal antibody B34D1.3 recognizes human podocalyxin, a protein expressed on undifferentiated human embryonic stem cells (ES), embryonic carcinoma cells (EC), and embryonic germ cells (EG). Podocalxyin is a heavily glycosylated cell adhesion protein with homology to CD34 and endoglycan. It was first identified on kidney podocytes, and then found to be upregulated in a variety of human cancers such as breast and prostate cancer. Like other stem cell-specific markers, the epitope recognized by the B34D1.3 antibody is lost upon cell differentiation. The B34D1.3 antibody recognizes the ectodomain of podocalyxin, which is a different epitope from the Tra-1-60 and Tra-1-81 monoclonal antibodies. While Tra1-60 has been found to react with a sialidase-sensitive epitope, the epitope recognized by Tra1-81 has not been fully defined.
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