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產品名稱:anti-human ABCG2 (CD338, Bcrp1, MXR) Biotin 5D3 25 ug
產品貨號:eBioscience 13-8888-80
產品規格:25 ug
Anti-Human CD338 (ABCG2) Biotin
Also known as: Bcrp1, MXR, ATP-binding cassette sub-family G member 2
Clone: 5D3
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 13-8888
Cat. No. Size
13-8888-80 25 ug
13-8888-82 100 ug
Description: The 5D3 monoclonal antibody reacts with the extracellular portion of the human ABCG2 protein, also known as Bcrp1 and MXR. The ABCG2 gene, a member of the multi-drug resistance (MDR) family, is highly expressed on primitive ‘side-population’ (SP) stem cells, which are defined by the efflux of fluorescent dyes such as Rhodamine 123 and Hoechest 33342. In the bone marrow, about 0.05% of cells display the low fluorescence and are highly enriched for repopulating cells. The SP cells, which express low or undetectable levels of CD34, have been identified in multiple species. In addition, expression of ABCG2 appears to be highly conserved.