產品名稱：anti-mouse TWEAK Biotin MTW-1 500 ug
產品貨號：eBioscience 13-9913-85
產品規格：500 ug
Anti-Mouse CD255 (TWEAK) Biotin
Also known as: TNF-related weak inducer of apoptosis, APO3L
Clone: MTW-1
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 13-9913
Cat. No. Size
13-9913-81  50 ug 
13-9913-82  100 ug 
13-9913-85  500 ug 
Description: The MTW-1 monoclonal antibody reacts with mouse TWEAK, a type II transmembrane TNF superfamily member with high identity to TNF in its extracellular portion. TWEAK transcript is expressed broadly in many ***** and fetal tissues. TWEAK is expressed as membrane bound and secreted forms. Interaction of TWEAK with its counter-receptor (Fn14, TWEAK-R) promotes secretion of IL-8, activation of NF-κB, proliferation of endothelial cells, and apoptosis in a number of human cell lines. Initially, DR3 was thought to be a receptor for TWEAK, but further studies have shown that TWEAK could induce apoptosis via receptors distinct from DR3. While TWEAK exhibits overlapping signaling functions to TNF, it is generally less effective in inducing apoptosis, giving rise to its name, TNF-like weak inducer of apoptosis.
 

產品留言

標題

聯系人

聯系電話

內容

驗證碼

點擊換一張

注：1.可以使用快捷鍵Alt+S或Ctrl+Enter發送信息!
2.如有必要,請您留下您的詳細聯系方式!