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eBioscience 14-0409-82 anti-human CD40 Purified 5C3 100 ug

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產品名稱: eBioscience 14-0409-82 anti-human CD40 Purified 5C3 100 ug
產品型號: 14-0409-82
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eBioscience 14-0409-82 anti-human CD40 Purified 5C3 100 ug


eBioscience 14-0409-82 anti-human CD40 Purified 5C3 100 ug  的詳細介紹
eBioscience 14-0409-82 anti-human CD40 Purified 5C3 100 ug

產品名稱:anti-human CD40 Purified 5C3 100 ug
產品貨號:eBioscience 14-0409-82
產品規格:100 ug
Anti-Human CD40 Purified
Also known as: TNFRSF5
Clone: 5C3
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-0409
Cat. No. Size
14-0409-80  25 ug 
14-0409-82  100 ug 
Description: The 5C3 monoclonal antibody reacts with human CD40, a 45-50 kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development and maturation by inducing Ig isotype-switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation. 5C3 is reported to be used for activation of B cells in in vitro functional assays.
 

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