Human CNTF receptor, alpha (clone AN-D3), **
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產品名稱: Human CNTF receptor, alpha (clone AN-D3), **
產品型號: 14-1304-82
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簡單介紹
Human CNTF receptor, alpha (clone AN-D3), **
Human CNTF receptor, alpha (clone AN-D3), **
的詳細介紹
Human CNTF receptor, alpha (clone AN-D3), **
產品名稱：Human CNTF receptor, alpha (clone AN-D3), 100 ug
產品貨號：eBioscience 14-1304-82
產品規格：100 ug
Anti-Human Ciliary Neurotrophic Factor Receptor alpha Purified
Also known as: CNTFRa, CNTF Receptor alpha, CNTF Ra
Clone: AN-D3
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-1304
Cat. No. Size
14-1304-80 25 ug
14-1304-82 100 ug
Description: This AN-D3 monoclonal antibody reacts with human ciliary neurotrophic factor receptor alpha (CNTFR alpha). CNTFR alpha expression is primarily localized to the nervous system and skeletal muscle. Together with gp130 and LIFR beta, this molecule forms the tripartite CNTF receptor complex. These receptor components remain unassociated until CNTF binds CNTFR alpha, which leads to their recruitment. Subsequent activation of the JAK-STAT pathway leads to changes in gene expression that affect cell survival and differentiation. More recently, another cytokine, neuropoietin, has been shown to bind the CNTFR receptor complex to promote nervous system development.
The AN-D3 antibody recognizes CNTFR alpha when it is dissociated from the tripartite complex.
