產(chǎn)品名稱：anti-mouse/human/chicken c-Myc p67 Purified 9E11 100 ug 產(chǎn)品貨號：eBioscience 14-6785-82 產(chǎn)品規(guī)格：100 ug Anti-c-Myc p67 Purified Also known as: cmyc Clone: 9E11 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-6785 Cat. No. Size 14-6785-80 25 ug 14-6785-82 100 ug Description: The 9E11 antibody reacts with mouse, human and chicken c-Myc; the antibody was, raised against a synthetic peptide, AEEQKLISEEDL (aa 408-420) of human c-myc. The transcription factor c-Myc is a proto-oncogene that is at the focal point in cell cycle regulation, metabolism, apoptosis, differentiation, cell adhesion, and tumorigenesis (1-3). In normal cells the expression of c-Myc is tightly regulated but in human cancers c-Myc is frequently deregulated (2&3).c-Myc also plays a pivotal role in apoptosis, most notably its connections to the CD95/Fas death receptor pathway (1&4). These different biological responses to c-Myc are most likely the result of different overlapping subsets of c-Myc target genes (1).
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