產(chǎn)品名稱：Purified anti-mouse/human RORg 100 ug 產(chǎn)品貨號：eBioscience 14-6988-82 產(chǎn)品規(guī)格：100 ug Anti-Human/Mouse ROR gamma (t) Purified Also known as: RORgamma, RORg, RORg(t), Retinoid-Related Orphan Receptor gamma, RORc Clone: AFKJS-9 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-6988 Cat. No. Size 14-6988-82 100 ug 14-6988-80 25 ug Description: The AJKJS-9 monoclonal antibody reacts with the mouse RORγ(t) protein. RORγ is a member of the retinoic acid-related orphan receptor (ROR) family, which also includes RORα and RORβ. ROR family proteins are ligand-dependent transcription factors that play roles in multiple physiological processes. RORγ is expressed in several tissues including liver, lung, muscle, heart and kidney. Furthermore, it was discovered that alternative transcription results in the expression of an isoform, RORγt, which is expressed exclusively in cells of the lymphoid compartment, namely CD4+CD8+ “double-positive” thymoyctes, Th17 cells of the periphery and lymphoid tissue inducer (Lti) cells of lymphoid organs. The RORγt isoform differs from RORγ by three unique amino acids at its amino terminus. Therefore, the AFKJS-9 antibody will react with both the RORγ and RORγt isoforms.
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