產品名稱：Mouse IL-19 Recombinant Protein 25 ug
產品貨號：eBioscience 14-8191-80
產品規格：25 ug
Mouse IL-19 Recombinant Protein
Also known as: IL19, Interleukin-19
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-8191
Cat. No. Size
14-8191-62  5 ug 
14-8191-80  25 ug 
Description: IL-19 is a recently-discovered member of the IL-10 superfamily of cytokines. It is expressed primarily by monocytes in response to LPS, IL-4, or GM-CSF. The IL-19 receptor complex is shared with IL-24 and IL-20 and is composed of the IL-20R1 and IL-20R2 subunits. IL-19 stimulates monocytes to produce IL-6 and TNF-α. It also triggers apoptosis and the production of reactive oxygen species. IL-19 has also been reported to upregulate Th2 cytokines in CD4+ T cells and to inhibit Th1 responses, such as IFN-γ expression. Elevated levels of IL-19 have been observed in asthmatic patients, further indicating a possible role for IL-19 in the differentiation of the Th2 lineage.

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