產品名稱：Affinity Purified Recombinant human MIF 25 ug
產品貨號：eBioscience 14-8500-80
產品規格：25 ug
Human MIF Recombinant Protein
Also known as: Macrophage migration inhibitory factor , Glycosylation-inhibiting factor, GIF, L-dopachrome isomerase, L-dopachrome tautomerase
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-8500
Cat. No. Size
14-8500-62  5 ug 
14-8500-80  25 ug 
Description: MIF (migration inhibitory factor, or macrophage migration inhibitory factor, MMIF) is an inflammatory mediator in response to bacterial lipopolysaccharide. MIF stimulates IL-1, IL-8 and MMP expression on fibroblasts. MIF stimulates NO and TNF-alpha production on macrophages. The secretion of MIF is regulated by steroids and MIF counter-regulates the immunosuppressive effects of steroids on immune response and cytokine induction. Therefore MIF plays an important role in endotoxemia and septic shock. The expression of MIF activity is correlated with delayed hypersensitivity and cellular immunity. It has been reported that the expression of MIF is significantly increased in cardiomyocytes in chronic hypoxia and the expression of MIF is implicated in cancer pathogenesis.
Human MIF is a non-glycosylated polypeptide consisting of 115 amino acids with a molecular weight of 12.5 kDa.

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