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產品名稱:Human EPO Recombinant Protein 25 ug
產品貨號:eBioscience 14-8992-80
產品規格:25 ug
Human Erythropoietin (EPO) Recombinant Protein
Also known as: EPO, Epoetin
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-8992
Cat. No. Size
14-8992-62 5 ug
14-8992-80 25 ug
Description: Erythropoietin (EPO) protein is a growth factor essential for the survival, proliferation, and differentiation of erythroid precursors. EPO is not responsible for early commitment to the lineage, and instead induces the final maturation of partially differentiated erythroid cells and the production of red cell-specific proteins, such as hemoglobin. The EPO receptor (EPOR) is present in higher levels on precursor cells, and expression diminishes with cell maturation.
Hepatocytes are the main source of EPO in the fetus, followed by interstitial cells of the kidney after birth and through *****hood. EPO expression is upregulated during hypoxia, and low levels of transcription have also been detected in lung and brain tissue under these conditions. Recent data suggest that EPO may also play a role in the protection of neuronal tissue from damage and initiation of repair.