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Anti-Human Hes1 Purified (4H1HES), **

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產品名稱: Anti-Human Hes1 Purified (4H1HES), **
產品型號: 14-9799-82
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Anti-Human Hes1 Purified (4H1HES), **


Anti-Human Hes1 Purified (4H1HES), **  的詳細介紹
Anti-Human Hes1 Purified (4H1HES), **

產品名稱:Anti-Human Hes1 Purified (4H1HES), 100 ug
產品貨號:eBioscience 14-9799-82
產品規格:100 ug
Anti-Human Hes1 Purified
Also known as: bHLHb39, Class B basic helix-loop-helix protein 39
Clone: 4H1HES1
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-9799
Cat. No. Size
14-9799-80  25 ug 
14-9799-82  100 ug 
Description: This 4H1HES monoclonal antibody reacts with human Hes1, a 30-kDa basic-helix-loop-helix transcriptional repressor. Hes1 is expressed in thymocytes, as well as neural, retinal, liver, and pancreatic tissues. Expression of Hes1 is controlled by Notch signaling, and thus plays an important role in T cell development. This regulation by Notch is also critical for neural stem cell differentiation and neurogenesis. Reports have demonstrated that Hes1 antagonizes transcription of MASH1, a basic-helix-loop-helix factor involved in neuronal determination. Finally, Hes1 has been associated with Notch-induced T cell acute lymphoblastic lymphoma and other cancers.

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