產品名稱：anti-human CD86 FG Purified IT2.2 500 ug
產品貨號：eBioscience 16-0869-85
產品規格：500 ug
Anti-Human CD86 (B7-2) Functional Grade Purified
Also known as: B72, B70
Clone: IT2.2
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 16-0869
Cat. No. Size
16-0869-81  50 ug 
16-0869-85  500 ug 
Description: The IT2.2 monoclonal antibody reacts with human CD86, an ~80 kDa surface receptor also known as B7-2. CD86 and CD80 are members of the B7 family of costimulatory molecules. CD86 is expressed at low levels on B cells, macrophages, and dendritic cells and is upregulated on B cells through a variety of surface stimuli including the BCR complex, CD40 and some cytokine receptors. In addition to CD80 (B7-1), CD86 is a counter-receptor for the T cell surface molecules CD28 and CD152 (CTLA-4). The interaction of CD86 with its ligands plays a critical role in T-B crosstalk, T cell costimulation, autoantibody production and Th2-mediated Ig production. The kinetics of upregulation of CD86 upon stimulation supports its major contribution during the primary phase of an immune response.

產品留言

標題

聯系人

聯系電話

內容

驗證碼

點擊換一張

注：1.可以使用快捷鍵Alt+S或Ctrl+Enter發送信息!
2.如有必要,請您留下您的詳細聯系方式!