Functional Grade Purified anti-human MDR1 (CD243, P-gp, P-glycoprotein, ABCB1)正
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產品名稱: Functional Grade Purified anti-human MDR1 (CD243, P-gp, P-glycoprotein, ABCB1)正
產品型號: 16-2439-85
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Functional Grade Purified anti-human MDR1 (CD243, P-gp, P-glycoprotein, ABCB1)**
Functional Grade Purified anti-human MDR1 (CD243, P-gp, P-glycoprotein, ABCB1)正
的詳細介紹
Functional Grade Purified anti-human MDR1 (CD243, P-gp, P-glycoprotein, ABCB1)**
產品名稱：Functional Grade Purified anti-human MDR1 (CD243, P-gp, P-glycoprotein, ABCB1) 500 ug
產品貨號：eBioscience 16-2439-85
產品規格：500 ug
Anti-Human CD243 (ABCB1) Functional Grade Purified
Also known as: P-glycoprotein-1, MDR1
Clone: UIC2
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 16-2439
Cat. No. Size
16-2439-81 50 ug
16-2439-85 500 ug
Description: This monoclonal antibody reacts with human Multidrug Resistant (MDR)-1, which is also known as P-glycoprotein (Pgp) and CD243. A 170-kDa transmembrane protein, MDR-1 is an ATP-dependent efflux pump for lipophilic compounds, including anti-cancer drugs. Expression of MDR-1 has been shown to correlate with multidrug resistance. In fact, tumor resistance to chemotherapy has been linked to MDR-1 expression in many cancers. MDR-1 is expressed in a variety of tissues, including the brain, kidney, liver, pancreas, and testes. Within the immune system, this molecule can be found on normal T, B, and natural killer cells, but not on monocytes.
This antibody has been reported to inhibit MDR1-mediated efflux.
