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產品名稱:anti-mouse F4/80 Antigen FG Purified BM8 1 mg
產品貨號:eBioscience 16-4801-86
產品規格:1 mg
Anti-Mouse F4/80 Antigen Functional Grade Purified
Also known as: F480, Pan Macrophage Marker
Clone: BM8
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 16-4801
Cat. No. Size
16-4801-85 500 ug
16-4801-86 1 mg
Description: The BM8 monoclonal antibody reacts with mouse F4/80 antigen, an approximately 125 kDa transmembrane protein. The F4/80 antigen is expressed by a majority of mature macrophages and is the best marker for this population of cells. However, other cell types such as Langerhans cells and liver Kupffer cells have been reported to express this antigen. Expression of F4/80 commences during early myeloid development and is upregulated on all BM cells stimulated in vitro with M-CSF. It has been shown that some cytokines downregulate the expression of F4/80 resulting in lack of F4/80 antigen on a subpopulation of macrophages, especially in the lymphoid microenvironment in vivo.