產品名稱：anti-human NKG2D / CD314 (activating) FG Purified 1D11 100 ug
產品貨號：eBioscience 16-5878-82
產品規格：100 ug
Anti-Human CD314 (NKG2D) Functional Grade Purified
Also known as: KLRK1
Clone: 1D11
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 16-5878
Cat. No. Size
16-5878-82  100 ug 
Description: The 1D11 monoclonal antibody reacts with the human NKG2D, a 42 kDa lectin-like molecule expressed by NK cells, γδ T cells, some CD4+ and CD8+ T cells. Human NKG2D forms complexes with DAP10, a membrane adaptor protein, and has the ability to costimulate multiple NK activation receptors. The counter-receptor for human NKG2D has been identified as MICA/MICB expressed on epithelial tumors from lung, breast, kidney, ovary, prostate and colon carcinoma. 5C6 and 1D11 block binding of soluble MICA to γδ TCR T cell clones and inhibit lysis by these cells. 5C6 and 1D11 induced NKG2D function of redirected lysis of FcReceptor bearing P815 cells.

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