產(chǎn)品名稱：Anti-Human TIGIT Functional Grade Purified (MBSA43) 500 ug 產(chǎn)品貨號：eBioscience 16-9500-85 產(chǎn)品規(guī)格：500 ug Anti-Human TIGIT Functional Grade Purified Also known as: VSTM3, WUCAM Clone: MBSA43 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 16-9500 Cat. No. Size 16-9500-82 100 ug 16-9500-85 500 ug Description: The MBSA43 monoclonal antibody reacts to human T cell immunoreceptor with Ig and ITIM domains (TIGIT), which is also known as VSTM3 or WUCAM. This 26 kDa protein is a member of the poliovirus receptor (PVR) family. The expression of TIGIT has been reported on NK cells, regulatory T cells, follicular T helper cells, memory CD4+ T cells, and CD8+ T cells, but it is not expressed on B cells or naïve CD4+ T cells. TIGIT may be upregulated on naïve CD4+ T cells upon activation. TIGIT can interact with certain members of the PVR and PVR-like families, including CD155, and also mediates the interaction of NK and T cells with antigen presenting cells, fibroblasts and endothelial cells that express PVR and PVR-like proteins.
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