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產品名稱:Functional Grade Human LAP (clone VB3A9), 100 ug
產品貨號:eBioscience 16-9823-82
產品規格:100 ug
Anti-Human LAP Functional Grade Purified
Also known as: latency-associated peptide, LAP-TGFb
Clone: VB3A9
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 16-9823
Cat. No. Size
16-9823-80 25 ug
16-9823-82 100 ug
Description: This VB3A9 monoclonal antibody recognizes human latency-associated peptide (LAP), also known as the TGF-β propeptide. Human LAP is a homodimer of 65-75 kDa that is non-covalently associated with TGF-β and this complex is also referred to as the small latent complex (SLC). LAP can be covalently associated with latent TGF-β binding proteins (LTBP) through disulfide bonds, forming the large latent complex (LLC). The association of LAP with TGF-β facilitates its secretion and also renders TGF-β inactive.
VB3A9 has been reported to cross-react with non-human primate LAP, but does not cross-react with mouse LAP.