產品名稱：Anti-Human CD49c (Integrin alpha 3) APC (P1B5) 100 tests
產品貨號：eBioscience 17-0494-42
產品規格：100 tests
Anti-Human CD49c (Integrin alpha 3) APC
Also known as: VLA3, ITGA3
Clone: P1B5
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 17-0494
Cat. No. Size
17-0494-41  25 tests 
17-0494-42  100 tests 
Description: This P1B5 monoclonal antibody reacts with human CD49c (also known as Integrin alpha 3). Integrins constitute a family of cell surface receptors that mediate adhesion between cells or between a cell and the extracellular matrix. These proteins are heterodimers consisting of two distinct subunits, α and β. Integrins are expressed on hematopoietic, non-hematopoietic, and cancer cells. Integrin-mediated adhesion is regulated by changes in ligand affinity (or activation), cell shape, and integrin clustering and diffusion. Integrin alpha 3 forms a complex with the common beta 1 subunit to form the α3β1 integrin. Studies have demonstrated the involvement of this integrin in wound healing and epithelial migration.
The P1B5 monoclonal antibody has been reported to affect adhesion to type I and VI collagens, as well as fibronectin and laminin.

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