產(chǎn)品名稱：Anti-Human CD66a (CEACAM1) (clone CD66a-B1.1) APC, 100 tests 產(chǎn)品貨號：eBioscience 17-0668-42 產(chǎn)品規(guī)格：100 tests Anti-Human CD66 APC Also known as: CEACAM1, CEACAM3, CEACAM6, CEA Clone: CD66a-B1.1 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 17-0668 Cat. No. Size 17-0668-41 25 tests 17-0668-42 100 tests Description: The CD66a-B1.1 monoclonal antibody reacts with human CD66a, c, d, and e, which are also known as CEACAM1, CEACAM6, CEACAM3 and CEA, respectively. CD66 is expressed on endothelial and epithelial cells, as well as on neutrophils and monocytes. Myeloma and cancer cells also express CD66. Moreover, expression of this receptor can be induced on T cells, B cells, and CD16-negative NK cells. CD66 exists as multiple splice variants that differ in the length of their cytoplasmic domain, which contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) that mediates the inhibitory functions of this cell surface protein on T and NK cells. CD66 is involved in cell adhesion and growth, neutrophil activation, and signaling. Finally, studies have shown that the CD66 variants interact with each other homo- and heterotypically.
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