產(chǎn)品名稱：Anti-Human CD169 (Siglec-1) APC (7-239), 100 tests 產(chǎn)品規(guī)格：eBioscience 17-1699-42 產(chǎn)品貨號(hào)：100 tests Anti-Human CD169 (Siglec-1) APC Also known as: Sialoadhesin Clone: 7-239 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 17-1699 Cat. No. Size 17-1699-41 25 tests 17-1699-42 100 tests Description: This 7-239 monoclonal antibody reacts with human CD169, also known as Siglec-1 and Sialoadhesin. This type I transmembrane protein is a member of the sialic acid binding Ig-like lectin (Siglec) family. Expressed on macrophages and dendritic cells in peripheral blood, lymph nodes, and spleen in humans, CD169 binds glycoproteins and glycolipids containing N-acetylneuraminyl alpha 2-3-galactose. CD169 expression can also be induced on CD14+ monocytes by interferon-alpha and interferon-gamma to mediate HIV-1 infection. Finally, CD169 has also been shown to be involved in antigen presentation to invariant NK T cells. This monoclonal antibody has been reported to inhibit erythrocyte binding to CD169-expressing cells.
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