產(chǎn)品名稱：APC Human ILT3 (clone ZM4.1), 100 tests 產(chǎn)品規(guī)格：eBioscience 17-5139-42 產(chǎn)品貨號(hào)：100 tests Anti-Human CD85k (ILT3) APC Also known as: LIR5, LILRB4, HM18, GM 4d Clone: ZM4.1 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 17-5139 Cat. No. Size 17-5139-41 25 tests 17-5139-42 100 tests Description: The monoclonal antibody ZM4.1 recognizes ILT3, also known as CD85k. ILT3 is a member of the large family of ILT molecules (Immunologulin-like Transcripts, Leucocyte Ig-like Receptors (LIRs) and Monocyte/Macrophage Ig-like Receptors (MIRs). ILT3 is a 60kDa transmembrane protein with two Ig domains and ITIMs. Expression is found on monocytes, macrophages, and dendritic cells. High levels of ILT3 expression is also found on plasmacytoid dendritic cells (pDCs). ILT3 expression by DCs has been shown to be required to induce Regulatory Tcells (tregs). Addition of ZM4.1, like ZM3.8, blocks the suppressive function of the Tregs in in vitro culture systems with allogenic DC’s.
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