產(chǎn)品名稱(chēng)：Recombinant Mouse IL-13 500 ug 產(chǎn)品貨號(hào)：eBioscience 34-8131-85 產(chǎn)品規(guī)格：500 ug Mouse IL-13 Recombinant Protein Carrier-Free Also known as: Interleukin-13, IL13 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 34-8131 Cat. No. Size 34-8131-82 100 ug 34-8131-85 500 ug Description: Mouse interleukin-13 (IL-13), originally designated p600, is a 11.6 kDa protein secreted by activated T helper cells, CD8+ T cells, and NK cells. IL-13 was originally identified in 1989 through differential hybridization of cDNA libraries prepared from T helper 1 and T helper 2 cells. IL-13 contains four cysteine residues, which form two intramolecular disulfide bonds. IL-13 shares many activities with IL-4; this relates to a requirement for IL-4Rα chain for signal transduction. The biological activities of IL-13 include suppression of macrophage cytotoxic activity, upregulation of IL-1RA expression, and suppression of inflammatory cytokine expression. IL-13 induces CD23 expression on B cells and enhances CD72, and expression of class II MHC gene products. Mouse IL-13 does not display the activities on T cells and B cell stimulatory effects which IL-4 exhibits. Mouse IL-13 is active on human and mouse cells.
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