產(chǎn)品名稱：Anti-Human CD122 PerCP-eFluor® 710 (9A2-CD122) 100 tests 產(chǎn)品貨號：eBioscience 46-1229-42 產(chǎn)品規(guī)格：100 tests Anti-Human CD122 PerCP-eFluor® 710 Also known as: Interleukin-2 Receptor beta, IL-2Rb, IL-2Rbeta p70, IL-2 receptor beta Clone: 9A2-CD122 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 46-1229 Cat. No. Size 46-1229-41 25 tests 46-1229-42 100 tests Description: This 9A2-CD122 monoclonal antibody reacts with human CD122, which is also known as interleukin-2 receptor beta (IL-2Rβ). This receptor is expressed on NK cells, activated T cells, some B cells, monocytes, and T cell leukemias. CD122 can also be detected during early NK cell commitment. IL-2Rβ associates with the IL-2Rα (CD25) or IL-15Rα and common γ chain (CD132) to form the high affinity IL-2 and IL-15 receptors, respectively. By itself, this membrane receptor can bind IL-2, but with intermediate affinity. The binding of IL-2 results in internalization of the cytokine, tyrosine phosphorylation of IL-2Rβ, and activation of signaling cascades such as the JAK/STAT pathway.
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