產品名稱：Anti-Human CD206 eFluor® 450 (19(19.2)) 100 tests 產品貨號：eBioscience 48-2069-42 產品規(guī)格：100 tests Anti-Human CD206 (MMR) eFluor® 450 Also known as: Mrc1 Clone: 19.2 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 48-2069 Cat. No. Size 48-2069-41 25 tests 48-2069-42 100 tests Description: This 19.2 monoclonal antibody reacts with human CD206, which is also known as the macrophage mannose receptor (MMR). CD206 is expressed on macrophages and dendritic cells. This type I transmembrane protein can also be detected on non-immune cells, including hepatic and lymphathic epithelia and kidney mesengial cells. CD206 binds to glycoproteins that terminate in D-mannose, L-fucose, or N-acetylglucosamine, as well as a variety of hormones. This receptor undergoes constitutive internalization and recycling between the plasma membrane and the endosomal compartment. CD206 is involved in antigen processing and presentation, cell migration, and intracellular signaling. Moreover, CD206 plays a key role in phagocytosis pathogens such as Candida albicans, Leishmania, and Mycobacterium tuberculosis.
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