產品名稱：eFluor™ 450 anti-human Foxp3 (Pacific Blue® Replacement) 100 tests 產品貨號：eBioscience 48-4801-82 產品規(guī)格：100 tests Anti-Mouse F4/80 Antigen eFluor® 450 Also known as: F480, Pan Macrophage Marker Clone: BM8 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 48-4801 Cat. No. Size 48-4801-80 25 ug 48-4801-82 100 ug Description: The BM8 monoclonal antibody reacts with mouse F4/80 antigen, an approximately 125 kDa transmembrane protein. The F4/80 antigen is expressed by a majority of mature macrophages and is the best marker for this population of cells. However, other cell types such as Langerhans cells and liver Kupffer cells have been reported to express this antigen. Expression of F4/80 commences during early myeloid development and is upregulated on all BM cells stimulated in vitro with M-CSF. It has been shown that some cytokines downregulate the expression of F4/80 resulting in lack of F4/80 antigen on a subpopulation of macrophages, especially in the lymphoid microenvironment in vivo.
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