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產品名稱:Anti-Human Fibronectin Alexa Fluor® 488 (FN-3) 100 ug
產品貨號:eBioscience 53-9869-82
產品規格:100 ug
Anti-Human Fibronectin Alexa Fluor® 488
Clone: FN-3
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 53-9869
Cat. No. Size
53-9869-80 25 ug
53-9869-82 100 ug
Description: The FN-3 monoclonal antibody recognizes human fibronectin, a component of the extracellular matrix. This high molecular weight protein (almost 400 kDa) exists as an extracellular and a soluble plasma form. Fibronectin functions in cell adhesion and migration via integrins present on the interacting cell. Fibronectin also associates with collagen, actin and fibrins. In malignancies, fibronectin protein levels can be altered. In lung carninomas, expression is decreased. The FN-3 antibody recognizes a determinant on human cellular but not plasma fibronectin; this recognition is not lost upon trypsin treatment. Furthermore, FN-3 antibody has been shown to crossreact to bovine fibronectin.