產品名稱：Foxp3 Whole Blood Staining Kit (with PE PCH101) 1
產品貨號：eBioscience 88-8996-40
產品規格：Kit
Human Regulatory T Cell Whole Blood Staining Kit
Also known as: Forkhead Box P3, Scurfin, JM2, Treg, Foxp3 PCH101 PE-Cy5; CD4 FITC; CD25 PE
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 88-8996
Cat. No. Size
88-8996-40  Kit 
Description: Regulatory T cells/Tregs (also known as suppressor T cells) are a specialized subpopulation of T cells that act to suppress immune responses thereby maintaining homeostasis and self tolerance. Intense investigation has tried to determine exclusive protein markers for Tregs. This has been complicated by the identification of four regulatory T cells subsets; natural, anergic, Tr1 and CD8+CD28- suppressor T cells. There are still no cell surface molecules that uniquely distinguish functional regulatory cells from conventional T cells. It has been proposed that the “natural” regulatory T cells originally recognized by their constitutive expression of CD4 and CD25 are further defined by expression of the transcription factor Foxp3. Additionally Foxp3 has also been characterized in CD8+CD28- suppressor T cells.
Not included:
Antibody or Isotype control for CD4 and CD25 (cocktails cat. 22-0425 and cat. 22-1714)

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