產(chǎn)品名稱：Calyculin A 產(chǎn)品貨號(hào)：LC C-3987 產(chǎn)品規(guī)格：1 MG SPECIAL HAZARD: TUMOR PROMOTER. Gloves and mask should be worn when using this compound. Care must be taken to prevent contact through all routes of exposure. NOTE: Do not expose to sunlight or fluorescent lights for extended periods. Storage: Store at or below -20 ºC in the dark. Solubility: Soluble in DMSO and ethanol; very poorly soluble in water; maximum solubility in plain water is estimated to be about 1-10 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility Disposal: A Very potent inhibitor (Ki = ca. 0.1 nM) with high specificity for the PP-1 and PP-2 classes of protein serine/threonine phosphatase. Ishihara, H., et al. "Calyculin A and okadaic acid: inhibitors of protein phosphatase activity." Biochem. Biophys. Res. Comm. 159: 871-877 (1989). Potent non-phorbol type tumor promoter. Suganuma, M., et al. "Calyculin A, an inhibitor of protein phosphatases, a potent tumor promoter on CD-1 mouse skin." Cancer Res. 50: 3521-3525 (1990). Please request Technical Note #19 for additional information. Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.
滬公網(wǎng)安備 31011002002623號(hào)
