產品名稱:Insulin, human ELISA 產 地:Demeditec 產品貨號:DE2935 產品規(guī)格:96 Tests 產品說明: Special remarks: Insulin is the principal hormone responsible for the control of glucose metabolism. It is synthesized in the ß-cells of the islets of Langerhans as the precursor, proinsulin, which is processed to form C-peptide and insulin. Both are secreted in equimolar amounts into the portal circulation. The mature insulin molecule comprises two polypeptide chains, the A chain and B chain (21 and 30 amino acids respectively). The two chains are linked together by two inter-chain disulphide bridges. There is also an intra-chain disulphide bridge in the A chain. Secretion of insulin is mainly controlled by plasma glucose concentration, and the hormone has a number of important metabolic actions. Its principal function is to control the uptake and utilisation of glucose in peripheral tissues via the glucose transporter. This and other hypoglycaemic activities, such as the inhibition of hepatic gluconeogenesis and glycogenolysis are counteracted by the hyperglycaemic hormones including glucagon, epinephrine (adrenaline), growth hormone and cortisol. Insulin concentrations are severely reduced in insulin-dependent diabetes mellitus (IDDM) and some other conditions such as hypopituitarism. Insulin levels are raised in non-insulin-dependent diabetes mellitus (NIDDM), obesity, insulinoma and some endocrine dysfunctions such as Cushing’s syndrome and acromegaly. 上海玉博生物技術有限公司在為生命科學領域提供豐富的產品與信息資源方面處于****地位,公司提供的產品涵蓋了二十多個國家近五十萬種產品,而且產品的數(shù)量與信息在不斷的增長和更新,公司提供的產品能夠使生命科學工作者加快對生物化學,分子生物學,細胞生物學以及蛋白質組學研究的認知,以及分子診斷和臨床醫(yī)學領域的應用。
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