產(chǎn)品名稱:CA 19-9 IRMA 產(chǎn) 地:Demeditec 產(chǎn)品貨號:DE4046 產(chǎn)品規(guī)格:96 Tests 產(chǎn)品說明: Special remarks: CLINICAL BACKGROUND CA 19-9, equivalent to Sialyl Lewis antigen, is a mucin type glycoprotein found in the blood repetitively bearing a carbohydrate epitope which is specifically recognized by the mouse monoclonal antibody, C192. CA 19-9 is an oncofetal antigen, expressed by several different cancers, but especially carcinomas of the gastrointestinal tract. It is present in the fetal epithelium of the stomach, intestine, liver and pancreas. CA 19-9 is a tumor marker for pancreatic, gallbladder, gastric and colorectal cancers. CA 19-9 can be used to track treatment progress of previously diagnosed cancer. This blood test in conjunction with periodic CT scans will show whether the cancer is in remission or is continuing to grow. However, it is more useful in measuring the effectiveness of cancer treatment by studying the patient’s CA 19-9 levels over time. There are benign diseases of the bile ducts and pancreas that occasionally result in elevated CA 19-9 levels and a low CA 19-9 level does not exclude the possible presence of a malignant tumor. For this reason, the determination of CA 19-9 concentrations is not considered as a diagnostic test. PRINCIPLES OF THE METHOD The Demeditec CA 19-9-IRMA is a two-step immunoradiometric assay based on coated?tube separation. Mab1, the capture antibody, is attached to the lower and inner surface of the plastic tube. Add calibrators or samples to the tubes. After incubation, washing removes the occasional excess of antigen. Addition of Mab2, the signal antibody labelled with 125I, will complete the system and trigger the immunological reaction. After washing, the remaining radioactivity bound to the tube reflects the antigen concentration. 上海玉博生物技術(shù)有限公司在為生命科學(xué)領(lǐng)域提供豐富的產(chǎn)品與信息資源方面處于****地位,公司提供的產(chǎn)品涵蓋了二十多個國家近五十萬種產(chǎn)品,而且產(chǎn)品的數(shù)量與信息在不斷的增長和更新,公司提供的產(chǎn)品能夠使生命科學(xué)工作者加快對生物化學(xué),分子生物學(xué),細胞生物學(xué)以及蛋白質(zhì)組學(xué)研究的認知,以及分子診斷和臨床醫(yī)學(xué)領(lǐng)域的應(yīng)用。
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