產品名稱：NSE IRMA
產    地：Demeditec 
產品貨號：DE4411
產品規格：96 Tests
產品說明：
Special remarks:
CLINICAL BACKGROUND
Biological activities
The glycolytic enzyme enolase (2-phospho-D-glycerate hydrolase, EC 4.2.1.11) exists as several dimeric isoenzymes (aa, ab, ag, bb and gg). The gg and ag enolase isoenzymes are also known as neuron- specific enolase (NSE) as they are produced in central and peripheral neurons and malignant tumors of neuroectodermal origin. Elevated serum concentrations of NSE are detected in patients with medullar carcinoma of the thyroid, pancreatic islet cell tumor, pheochromocytoma carcinoid, neuroblastoma and small-cell lung carcinoma (SCLC).
Clinical applications
The diagnosis of lung cancer generally requires medical imaging, endoscopy, intra-operative findings and histology. An important indication for tumor marker determinations in lung cancer is in assessing the efficacy of therapy and post-operative follow-up care. In patients with SCLC, serum levels of NSE reflect the response to chemotherapy.
PRINCIPLES OF THE METHOD
The Demeditec NSE-IRMA is an immunoradiometric assay based on coated-tube separation. Mab1, the capture antibody, is attached to the lower and inner surface of the plastic tube. Calibrators or samples added to the tubes will at first show low affinity for Mab1. Addition of Mab2, the signal antibody labelled with 125I, will complete the system and trigger the immunological reaction. After washing, the remaining radioactivity bound to the tube reflects the antigen concentration.
上海玉博生物技術有限公司在為生命科學領域提供豐富的產品與信息資源方面處于****地位，公司提供的產品涵蓋了二十多個國家近五十萬種產品，而且產品的數量與信息在不斷的增長和更新，公司提供的產品能夠使生命科學工作者加快對生物化學，分子生物學，細胞生物學以及蛋白質組學研究的認知，以及分子診斷和臨床醫學領域的應用。

產品留言

標題

聯系人

聯系電話

內容

驗證碼

點擊換一張

注：1.可以使用快捷鍵Alt+S或Ctrl+Enter發送信息!
2.如有必要,請您留下您的詳細聯系方式!