產品名稱：Progesterone RIA
產    地：Demeditec
產品貨號：DE4494
產品規格：96 Tests
產品說明：
Special remarks:
Biological Activity
Progesterone is a C?21 steroid hormone (molecular weight: 314.5) which is synthesized from cholesterol via pregnenolone in the granulosa and theca cells of the corpus luteum under the influence of LH. The major production sites are ovary and placenta and somewhat the adrenal cortex in both men and women. Progesterone is rapidly metabolized in the liver. Blood levels are very low during the follicular phase whereas one does observe a sharply increase during the luteal phase of menstrual cycles reaching a maximum some 5 to 10 days after the midcycle LH peak.
Clinical applications
Serum progesterone levels, which are low during the follicular phase, increase during the luteal phase of menstrual cycle. Unless pregnancy occurs, the progesterone level declines 4 days before the next menstrual period. Thus, the measurement of progesterone levels constitutes a well?established method for detection of ovulation. But there are many cases where the progesterone measurements are also of interest:
- To check the effectiveness of ovulation induction;
- To monitor the embryo transfer and progesterone replacement therapy;
- To detect the patients at risk for abortion during the beginning of pregnancy;
- To aid in the diagnostic of ectopic pregnancy;
- To detect all ovarian tumor (benign and malign) in postmenopausal women;
-  To diagnose luteinized unruptured follicle by the dosage of 17 beta?estradiol   and progesterone levels in peritoneal fluid;
- The steroid profiles of follicular fluids and the ratio of E2/PROG allow detecting a normal or a dysfunctional ovulation induction. (The empty follicular syndrome may reflect a dysfunctional ovulation induction).
The above test kits measures the total (unconjugated) Progesterone in serum. There is also a method available for the measurement of free Progesterone in saliva. The metabolic activity of any steroid is just represented by the free hormone fraction which represents less than 5% of the total. The non-invasive sampling of saliva samples offers another advantage of salivary testing. Demeditec is offering such a testkit in ELISA format with the catalogue number DES6633.
上海玉博生物技術有限公司在為生命科學領域提供豐富的產品與信息資源方面處于****地位，公司提供的產品涵蓋了二十多個國家近五十萬種產品，而且產品的數量與信息在不斷的增長和更新，公司提供的產品能夠使生命科學工作者加快對生物化學，分子生物學，細胞生物學以及蛋白質組學研究的認知，以及分子診斷和臨床醫學領域的應用。

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