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hCG-b, free ELISA

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產品名稱: hCG-b, free ELISA
產品型號: DE4718
產品展商: 原裝進口
產品文檔: 無相關文檔

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hCG-b, free ELISA


hCG-b, free ELISA  的詳細介紹
hCG-b, free ELISA

產品名稱:hCG-b, free ELISA
產    地:Demeditec 
產品貨號:DE4718
產品規格:96 Tests
產品說明:
Special remarks: Relation between ng and international units (IU).
1 ng of free β-hCG equals to 0.1 m IU in terms of hCG immunological activity.
This testkit replaces the former one coded DE1793.
Human Chorionic Gonadotropin (hCG) is a glycoprotein hormone normally produced by placenta during pregnancy. The hormone is present in blood and urine around seven to thirteen days following implantation of the fertilized ovum. Structurally intact hCG molecules consist of two non-covalently linked polypeptide subunits, the alpha and beta chain subunits. Measurement of intact hCG and of the alpha subunit of hCG appears to give similar results in blood and urine but not the levels of beta subunit.
In normal second-trimester maternal sera, the level of intact hCG ranges from 20,000 mlU/ml to 50,000 mlU/ml. In contrast, the levels of either free - or free ß-hCG are on average one half of 1% of hCG levels. hCG and the free subunits appear not to be useful as serological markers for nontrophoblastic tumors; however, the absolute increase of ß-hCG level in choriocarcinoma patients clearly differentiates it from normal pregnancy.
Recent studies showed a signifieant inerease in the level of free ß-hCG subunit in trisomy 21 cases as compared with controls. Hence it has been suggested that free ß-hCG subunit assay in a combination of maternal serum AFP could be effective in a screening protocol for trisomy 21.
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