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Lipoprotein (a) ELISA

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產品名稱: Lipoprotein (a) ELISA
產品型號: DE7700040
產品展商: 原裝進口
產品文檔: 無相關文檔

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Lipoprotein (a) ELISA


Lipoprotein (a) ELISA  的詳細介紹
Lipoprotein (a) ELISA

產品名稱:Lipoprotein (a) ELISA
產    地:Demeditec 
產品貨號:DE7700040
產品規格:96 Tests
產品說明:
Special remarks:
Lipoprotein(a) [Lp(a)] is a genetically determined andindependent risk factor for atherosclerosis. Little is knownabout physiological function and metabolism of Lp(a). Theserum concentration of this lipoprotein may vary between0-200 mg/dl.At concentrations exceeding 30 mg/dl the riskfor the development of atherosclerosis is markedlyincreased, particularly when there is a synchronousincrease of the LDL-cholesterol.The structure of Lp(a) is derived from the structure of theLDL particle. Lp(a) is a LDL particle, which is bound to thehighly glycosylated apolipoprotein(a) [apo(a)] through oneor more disulphide bridges. Homologies in the sequencesof apo(a) and plasminogen indicate a correlation betweenthrombotic and atherosclerotic processes.The protein and lipid composition of Lp(a) is characterizedby inter- as well as intraindividual heterogeneity. More than 30 isoforms have been characterized so far. It is not known whether this heterogeneity influences the relative risk for the development of atherosclerosis.In contrast to other lipoproteins, the concentrations of Lp(a) cannot be influenced by dietary measures. Lipid lowering drugs, which reduce the LDL concentration, have no effect on Lp(a).
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