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Osteocalcin human ELISA

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產品名稱: Osteocalcin human ELISA
產品型號: DEKAP1381
產品展商: 原裝進口
產品文檔: 無相關文檔

簡單介紹

Osteocalcin human ELISA


Osteocalcin human ELISA  的詳細介紹
Osteocalcin human ELISA

產品名稱:Osteocalcin human ELISA
產    地:Demeditec 
產品貨號:DEKAP1381
產品規格:96 Tests
產品說明:
Special remarks: This testkit allows the quantitative measurement of intact human osteocalcin in human serum and plasma (heparin or EDTA) samples. There is no cross reactivity with N- or C-terminal fragments.
Osteocalcin, the major non-collagenous protein of bone, is a specific product of the osteoblast and its synthesis is stimulated by 1,25-Dihydroxy vitamin D3 .  A fraction of that synthesized does not accumulate in bone but is secreted directly into the circulation.  Animal studies indicate serum osteocalcin is derived from new cellular synthesis rather than from the release of bone matrix protein during resorption.  Furthermore, serum osteocalcin concentrations are related to histomorphometric measurements of bone formation but not resorption.  Deviations from normal concentrations of circulating osteocalcin are a consequence of changes in the synthesis or degradation of the protein.  Such changes may result from or may be associated with specific disease states.  While the precise biological function of osteocalcin is not known, it is the most specific marker of osteoblastic function described to date.
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