產品名稱：Endothelin-1 ELISA
產    地：Demeditec 
產品貨號：JP27165
產品規格：96 Tests
其它產品：
Endothelin-1 (Big)  Demeditec JP27168 96 Tests 9218
Endothelin-3 Demeditec JP27169 96 Tests 9218
產品說明：
Special remarks:
Can be used for humans but also for bovine, canine, murine, porcine, rabbit, rat investigations, as the amino acid sequence of Endothelin-1 in these animals is the same like in humans.
Cross rectivity to Endothelin-3 is 0,1%, all other Endothelins < 0,1%
Endothelin-1 (ET-1), a peptide of 21 amino acid residues, is the most potent vasoconstrictor substance known.  The discovery by Rubanyi’s group in 1985 of a peptide termed endothelium-derived contracting factor (EDCF) and the isolation, sequencing, cloning and naming endothelin by Yanagisawa of the most potent vasoconstrictor has led to more understanding of many physiological effects.  ET-1 is known to be one of a family of three mammalian vasoactive peptides including endothelin-2 (ET-2) and endothelin-3 (ET-3).  These related peptides differ from ET-1 at the two and six amino acid residue positions, respectively.  Those genes make three pre-propeptides that are cleaved into three big endothelin molecules, each 39 amino acid long.  A number of reviews of function, molecular biology of the endothelin family of peptides and propeptides are available.  ET-1 has been shown to have potent effects on smooth muscle cells, fibroblasts and to be involved in many disease processes, particularly cardiovascular diseases.  It has been shown to be important in congestive heart failure, renal failure and pulmonary hypertension.
上海玉博生物技術有限公司在為生命科學領域提供豐富的產品與信息資源方面處于****地位，公司提供的產品涵蓋了二十多個國家近五十萬種產品，而且產品的數量與信息在不斷的增長和更新，公司提供的產品能夠使生命科學工作者加快對生物化學，分子生物學，細胞生物學以及蛋白質組學研究的認知，以及分子診斷和臨床醫學領域的應用。

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