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Corticosterone rat/mouse ELISA

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產品名稱: Corticosterone rat/mouse ELISA
產品型號: DEV9922
產品展商: 原裝進口
產品文檔: 無相關文檔

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Corticosterone rat/mouse ELISA


Corticosterone rat/mouse ELISA  的詳細介紹
Corticosterone rat/mouse ELISA

產品名稱:Corticosterone rat/mouse ELISA
產    地:Demeditec 
產品貨號:DEV9922
產品規格:96 Tests
產品說明:
Special remarks:
Introduction
Physiology
Corticosterone is the principle glucocorticoid secreted by the adrenal cortices of mice and rats. Secretion of corticosterone in these species is modulated by a complex negative feedback mechanism involving the central nervous system, hypothalamus, pituitary, and adrenals. ACTH released from the pituitary augments adrenal secretion of corticosterone while falling levels of corticosterone are associated with rising levels of ACTH. In both mice and rats there is a circadian rhythm of corticosterone release with the highest concentrations being observed between 1600 and 2200 hours in a normal laboratory environment.
Laboratory Applications
Corticosterone measurements are a useful index of general and neuroendocrine response to the stress of laboratory experiments in mice and rats. Thus corticosterone concentrations rise sharply in healthy, intact animals following exposure to experimental stimuli such as drugs, barometric shock, experimental disease state, or abrupt temperature shifts, and may serve to document the neuroendocrine and endocrine integrity of the preparation while observations are being made.
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