產品名稱：N-ERC/Mesothelin mouse ELISA
產    地：Demeditec 
產品貨號：JP27783
產品規格：96 Tests
產品說明：
Special remarks:
INTRODUCTION
Erc has been identified as a gene showing stronger expression in cancer-affected renal tissue than in normal renal tissue in Eker rats (a rat model of renal cancer).
The  human  homologue  of  the  protein  encoded  by  this  gene  is  called  MPF (megakaryocyte potentiating factor) or mesothelin. This protein is detected especially prominently in mesothelial cells, and its involvement has been suggested in  the  development  of  mesothelioma,  making  it  a promising  tumor  marker.  In humans, involvement of this protein has also been suggested in the development of pancreatic, ovarian and pulmonary cancers, etc. The protein is expressed as a GPI anchor-type  membranous  protein (about  71  kDa  in  molecular  weight),  which  is thought to be digested by a furin-like protease to yield fragments about 31 kDa and 40 kDa in size.
We think it is helpful for research of ERC/Mesothelin protein and have characterized the 31 kDa fragment as N-ERC/Mesothelin and the 40 kDa fragment as C-ERC/Mesothelin. This ELISA kit can measure Mouse N-ERC/Mesothelin.
PRINCIPLE
This kit is a solid phase sandwich ELISA using 2 kinds of highly specific antibodies. Tetra  Methyl  Benzidine  (TMB)  is  used  as  a  coloring  agent  (Chromogen).  The strength of coloring is proportional to the quantities of Mouse N-ERC/Mesothellin.
上海玉博生物技術有限公司在為生命科學領域提供豐富的產品與信息資源方面處于****地位，公司提供的產品涵蓋了二十多個國家近五十萬種產品，而且產品的數量與信息在不斷的增長和更新，公司提供的產品能夠使生命科學工作者加快對生物化學，分子生物學，細胞生物學以及蛋白質組學研究的認知，以及分子診斷和臨床醫學領域的應用。

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