產(chǎn)品名稱：alpha-2,6-Sialyltransferase ELISA 產(chǎn) 地：Demeditec 產(chǎn)品貨號：JP27762 產(chǎn)品規(guī)格：96 Tests 產(chǎn)品說明： Special remarks: The antiserum in this assay also cross reacts with mouse and rat. JP27762: recognizes the C-terminal and middle part of alpha-2,6-Sialyltransferase, common in human, rat and mouse. It can detect both of intact form and forms lacked N-terminal side parts. The histopathological picture of Alzheimer's disease is characterized by senile plaques and neurofibrillary tangles, and because the senile plaques form first, they are considered the initial lesion. Senile plaques are known to be formed by accumulation of beta-amyloid peptide (Abeta). Abeta peptide is produced by the cleavage of amyloid precursor protein (APP) by two types of proteolytic enzymes. The first cleavage is performed by beta-secretase (BACE1), and the second gamma-secretase. It is thought that their inhibitors may be capable of serving as safe drugs for the treatment of Alzheimer's disease. In recent years a glycosyltransferase involved in the biosynthesis of sugar chains (alpha 2,6-sialyltransferase) has also been shown to be cleaved by BACE1. The cleavage site was identified at the same time, and as a result it was demonstrated that in rats it produces cleavage-type alpha 2,6-sialyltransferase (E41 Form). This product is a measurement kit that enables detection of human, rat and mouse alpha 2,6-sialyltransferase. 上海玉博生物技術有限公司在為生命科學領域提供豐富的產(chǎn)品與信息資源方面處于****地位，公司提供的產(chǎn)品涵蓋了二十多個國家近五十萬種產(chǎn)品，而且產(chǎn)品的數(shù)量與信息在不斷的增長和更新，公司提供的產(chǎn)品能夠使生命科學工作者加快對生物化學，分子生物學，細胞生物學以及蛋白質(zhì)組學研究的認知，以及分子診斷和臨床醫(yī)學領域的應用。
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